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Test Code TREGS T-Cell Subsets, Regulatory (Tregs), Blood

Reporting Name

T Cell Subsets, Regulatory (Tregs)

Useful For

Evaluating patients with clinical features of IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked inheritance) and other primary immunodeficiencies, autoimmune diseases, allergy and asthma, and graft-vs-host disease post-hematopoietic stem cell transplantation

Method Name

Flow Cytometry

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole Blood EDTA


Shipping Instructions


Testing performed Monday through Friday. Specimens not received by 4 p.m. Central time on Fridays may be canceled

 

Specimens arriving on the weekend and observed holidays may be canceled.

 

Collect and package specimen as close to shipping time as possible. It is recommended that specimens arrive within 24 hours of collection.



Necessary Information


The ordering healthcare professional's name and phone number are required.



Specimen Required


Container/Tube: Lavender top (EDTA)

Specimen Volume: 3 mL

Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.

Additional Information: For serial monitoring, it is recommended that specimens are collected at the same time of day.


Specimen Minimum Volume

1 mL

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood EDTA Ambient 72 hours PURPLE OR PINK TOP/EDTA

Reference Values

The appropriate age-related reference values will be provided on the report.

Day(s) Performed

Monday through Friday

CPT Code Information

86359

86361

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TREGS T Cell Subsets, Regulatory (Tregs) 90413-6

 

Result ID Test Result Name Result LOINC Value
609282 CD4 (T Cells) 24467-3
29143 % Activated CD4+ T cells (4+CD25+) 13332-2
29144 % Natural Tregs 89320-6
29145 % N. Naive Tregs 89319-8
29146 % CD4+CD25-CD127+ (Tr1/Th3) 89318-0
29147 Activated CD4+ T cells (4+CD25+) 26982-9
29148 CD4+CD25+CD127loCD45RO+ (Nat Tregs) 89316-4
29149 CD4+CD25+CD127loCD45RA+ Naive Tregs 89315-6
29150 CD4+CD25-CD127+ (Tr1/Th3) 89317-2
29177 Interpretation 69052-9

Test Classification

This test was developed using an analyte specific reagent. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.

Report Available

3 to 4 days