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HelpTest Code MTDNU Methadone Confirmation, Random, Urine
Reporting Name
Methadone Confirmation, UUseful For
Monitoring for compliance of methadone treatment for analgesia or drug rehabilitation
Assessing compliance with rehabilitation programs by urine measurement of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine
Method Name
Gas Chromatography Mass Spectrometry (GC-MS) Confirmation with Quantitation
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineOrdering Guidance
1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order MTDNX / Methadone Confirmation, Chain of Custody, Random, Urine.
2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.
3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Container/Tube: Plastic, 10-mL urine tube
Specimen Volume: 10 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Specimen Minimum Volume
2.5 mL
Reject Due To
| Gross hemolysis | OK |
| Gross icterus | OK |
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 14 days |
Reference Values
Negative
Cutoff concentrations:
METHADONE BY GC-MS
<100 ng/mL
2-ETHYLIDENE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE GC-MS
<100 ng/mL
Day(s) Performed
Tuesday, Thursday
CPT Code Information
80358
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MTDNU | Methadone Confirmation, U | 104626-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 56028 | EDDP-by GC-MS | 104627-5 |
| 83129 | Methadone-by GC-MS | 104628-3 |
| 21107 | Methadone Interpretation | 69050-3 |
| 21110 | Chain of Custody | 77202-0 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Report Available
3 to 7 daysForms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.