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Test Code CMAT Chromosomal Microarray, Tumor, Fresh or Frozen

Useful For

Genomic characterization of tumor for copy number imbalances and loss of heterozygosity

 

Assisting in the diagnosis and classification of malignant neoplasms, including hematolymphoid malignancies

 

Evaluating the prognosis for patients with malignant tumors

Testing Algorithm

DNA is extracted from the specimen prior to hybridization to the microarray.

Method Name

Chromosomal Microarray (CMA)

Reporting Name

Chromosomal Microarray, Tumor

Specimen Type

Varies


Ordering Guidance


This test is not performed on formalin-fixed, paraffin-embedded (FFPE) specimens. If testing is needed for FFPE specimens, order CMAPT / Chromosomal Microarray, Tumor, Formalin-Fixed Paraffin-Embedded.

 

If an FFPE specimen is submitted, this test will be canceled and CMAPT / Chromosomal Microarray, Tumor, Formalin-Fixed Paraffin-Embedded will be added and performed as the appropriate test.



Additional Testing Requirements


 



Shipping Instructions


Advise Express Mail or equivalent if not on courier service.



Necessary Information


1. A reason for testing must be provided for testing to be performed.

2. A pathology report should accompany the specimen. If this information is not available at the time of order, submit as soon as possible for appropriateness of testing and to aid in interpretation of results.



Specimen Required


Submit only 1 of the following specimens:

Supplies: Hank's Solution (T132)

 

Specimen Type: Tumor biopsy

Container/Tube: Sterile container with sterile Hank's balanced salt solution, Ringer's solution, or normal saline

Specimen Volume: 0.5-3 cm(3) or larger

 

Specimen Type: Lymph node

Container/Tube: Sterile container with sterile Hank's balanced salt solution, Ringer's solution, or normal saline.

Specimen Volume: 1 cm(3)

 

Specimen Type: Skin biopsy

Container/Tube: Sterile container with sterile Hank's balanced salt solution, Ringer's solution, or normal saline.

Specimen Volume: 4-mm diameter

Collection Instructions:

1. Wash biopsy site with an antiseptic soap.

2. Thoroughly rinse area with sterile water.

3. Do not use alcohol or iodine preparations.

4. A local anesthetic may be used.

5. Biopsy specimens are best taken by punch biopsy to include full thickness of dermis.


Specimen Minimum Volume

Tumor biopsy: 3 cm(3); Lymph node: 1 cm(3); Skin biopsy: 4 mm diameter

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
  Refrigerated 

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

An interpretive report will be provided.

Day(s) Performed

Monday through Sunday

Report Available

10 to 21 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

81277

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CMAT Chromosomal Microarray, Tumor 94087-4

 

Result ID Test Result Name Result LOINC Value
54729 Result 62356-1
54730 Nomenclature 62356-1
54728 Result Summary 50397-9
54731 Interpretation 69965-2
CG905 Reason for Referral 42349-1
54743 Specimen 31208-2
54732 Source 31208-2
54733 Method 85069-3
53424 Additional Information 48767-8
54734 Released By 18771-6