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Test Code AMPHM Amphetamine-Type Stimulants Confirmation, Meconium

Reporting Name

Amphetamines, Confirmation, M

Useful For

Detecting in utero exposure to amphetamine-type stimulants up to 5 months before birth

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Meconium


Ordering Guidance


For chain-of-custody testing, order AMPMX / Amphetamine-Type Stimulants Confirmation, Chain of Custody, Meconium.



Specimen Required


Supplies: Stool container, Small (Random), 4 oz (T288)

Container/Tube: Stool container

Specimen Volume: 1 g (approximately 1 teaspoon)

Collection Instructions: Collect entire random meconium specimen.


Specimen Minimum Volume

0.3 g (approximately 1/4 teaspoon)

Reject Due To

Grossly bloody Reject; Pink OK
Stool
Diapers		 Reject

Specimen Stability Information

Specimen Type Temperature Time Special Container
Meconium Frozen (preferred) 28 days
  Ambient  28 days
  Refrigerated  28 days

Reference Values

Negative

Positives are reported with a quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) result.

 

Cutoff concentrations for LC-MS/MS testing:

Amphetamine: 20 ng/g

Methamphetamine: 20 ng/g

3,4-Methylenedioxyamphetamine: 20 ng/g

3,4-Methylenedioxyethylamphetamine: 20 ng/g

3,4-Methylenedioxymethamphetamine: 20 ng/g

Day(s) Performed

Monday through Sunday

CPT Code Information

80324

80359

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AMPHM Amphetamines, Confirmation, M 69021-4

 

Result ID Test Result Name Result LOINC Value
31854 Amphetamine 43934-9
31855 Methamphetamine 69022-2
31856 3,4-methylenedioxyamphetamine 69023-0
31858 3,4-methylenedioxyethylamphetamine 69024-8
31857 3,4-methylenedioxymethamphetamine 69025-5
31882 Interpretation 69050-3
31883 Chain of Custody 77202-0

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 to 3 days

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.